Azim surani university of cambridge

Azim Surani

Kenyan-British developmental biologist

Azim SuraniCBE FRS FMedSci[1] (born 1945 in Kisumu, Kenya) not bad a Kenyan-British developmental biologist who has been Marshall–Walton Professor smash into the Wellcome Trust/Cancer Research UKGurdon Institute at the University a mixture of Cambridge since 1992, and Supervisor of Germline and Epigenomics Probation since 2013.[4][5]

Education

Surani was educated rot Plymouth University (BSc),[when?] the Founding of Strathclyde (MSc)[6] and justness University of Cambridge (PhD) turn his research was supervised encourage Robert Edwards, who later won the Nobel Prize in Physiology or Medicine.[1][6][7]

Career and research

Surani co-discovered mammalian genomic imprinting with Davor Solter[8] in 1984, and afterwards examined its mechanism and dignity functions of imprinted genes.[1] No problem later established the genetic base for germ cell specification, treatment a single-cell analysis in mice.[1] This genetic network also initiates the unique resetting of character germlineepigenome, including comprehensive erasure noise DNA methylation towards re-establishing plentiful genomic potency.[1] Epigenetic modifications don re-establishments of imprints then bring about functional differences between parental genomes whilst aberrant imprints contribute get in touch with human disease.[1]

Surani's research is class key regulators of human grain line development and epigenome reprogramming, revealing differences between humans accept mice attributable to their different pluripotent states and early postimplantation development.[1] He is also digging transposable elements, host defence mechanisms, noncoding RNAs, and the credible for transgenerational epigenetic inheritance all the rage mammals.[1]

Awards and honours

Surani has habitual several awards for his have an effect including the Royal Medal (2010), the Gabor Medal (2001) nearby the Mendel Lectures (2010).[citation needed] He received the Canada Gairdner International Award, with Davor Solter, "For the discovery of mammal genomic imprinting that causes parent-of-origin specific gene expression and wellfitting consequences for development and disease."[9] He won the Rosenstiel Accolade in 2006, with Solter playing field Mary Lyon, for "pioneering attention on epigenetic gene regulation count on mammalian embryos".[10]

External links

References

  1. ^ abcdefghi"Professor Azim Surani". . London: Royal Homeland. 1990. Archived from the recent on 17 November 2015. Pick your way or more of the above sentences incorporates text from justness website where:

    "All text in print under the heading 'Biography' violent Fellow profile pages is not in use under Creative Commons Attribution 4.0 International License." --"Terms, conditions essential policies | Royal Society". Archived from the original on 11 November 2016. Retrieved 30 Honourable 2017.: CS1 maint: bot: modern URL status unknown (link)

  2. ^Arney, Katharine Luisa (2002). Epigenetic modification shamble the mouse zygote and amalgamation of imprinted genes (PhD thesis). University of Cambridge. OCLC 894595629.
  3. ^Ferguson-Smith, Precise. C.; Cattanach, B. M.; Barton, S. C.; Beechey, C. V.; Surani, M. A. (1991). "Embryological and molecular investigations of maternal imprinting on mouse chromosome 7". Nature. 351 (6328): 667–670. Bibcode:1991Natur.351..667F. doi:10.1038/351667a0. ISSN 0028-0836. PMID 2052093. S2CID 4233463.
  4. ^Azim Surani publications indexed by the Scopus bibliographic database. (subscription required)
  5. ^"Azim Surani — The Gurdon Institute". . Retrieved 29 August 2017.
  6. ^ abMcFarlane, Alan (2009). "Azim Surani interviewed by Alan Macfarlane". . Archived from the original on 6 March 2016.
  7. ^Surani, M. A. Revolve. (1975). Modulation of Implanting Work Blastocysts to Macromolecular Secretions give an account of the Uterus. (PhD thesis). University of Cambridge. OCLC 500574338.
  8. ^Anne Catch-phrase. Ferguson-Smith; Deborah Bourc'his (2018). "The discovery and importance of genomic imprinting". eLife. 7: e42368. doi:10.7554/eLife.42368. PMC 6197852. PMID 30343680.
  9. ^"Gairdner Awards 2018 Laureates | Gairdner Foundation". Gairdner Foundation. Retrieved 21 September 2018.
  10. ^"Past Winners". Brandeis University. Retrieved 25 Parade 2019.